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» Obscura Records - Strip about a record store in the Village in New York City. A look at the lives of the four young people who work there and what occurs around their jobs.
» Odd Jobs - David DiAngelo's modern day strip Odd Jobs.
» Off the Beat - Humorous strip written and drawn by Emily K, about kids involved with band and music.
» Off the Mark - Mark Parisi's daily comic panel is on the web with a daily cartoon, archives according to subject, some stuff to buy and syndication information.
» Offbeat - Cartoonist Gary Clair's gag panel comic strip.
» Ogga the Cane Toad - Black and white comic strip about a surfing toad, set in Queensland Australia. Drawn by Matthew Taylor.
» Oh My Gods! - A Pagan-based comic for the polythestic masses.
» Old Motherboard's Tranquillity Haven - Computer-related comics, cartoons and general humor by Roger Penwill.
» Onion Head Monster - Strange comics and animations about this misunderstood monster. By Paul Friedrich.
» Orval - Orval the pig is the star of this comic strip which runs weekly in the Arkansas Times. Politics and culture are lampooned.
» Oscar Quill and Coyle - Anthropomorphic strip about a college cartoonist and the stuff that happens to him. Occasionally peculiar. By Scott Elyard.
» OsigmaComics - Features webcomic about a school in the UK featuring all the stereotypical characters and situations like world domination.
» Otaku Life - An online comic strip about the secret life of college students and anime freaks. By Jeanette Brown.
» Otter Girl - Comix featuring Otter Girl by Emma Stone. Also: Flash animation and a rainy day clipping project.
» Out of My Mind - Regular comics, editorial cartoons and Web-A-Toons (web-only cartoons using animated gifs, and backgrounds) by Vikram Madan.
» Outta Toon - The official web site of the humor comic strip Outta Toon.
» Over the Hedge - Official website for the Over the Hedge comic strip.
» Over My Head - A sampling of this single panel comic.
» Over The Edge - Daily Web panel cartoon by Dan Reynolds. With selected past cartoons archived, and originals, cards and t-shirts to buy.
» Over the Edge - A gallery by cartoonist Tom Vogel. Original Cartoons are also for sale.
» Ozy and Millie - Two young foxes endure the trials and tribulations of childhood.
» Spoil Sports - Sports cartoons by Dominic Nunziato. A sports column in every cartoon.
» Tapestry: Over The Hedge - Daily comics.
» The Outer Burrows - Surreal humor strip using found images, by Atrowbri and Zillno.